Stress and Anti-depressants

Quite an interesting article on stress and depression. Or more to the point, stress and anti-depressants.

The experiment was performed on mice, so may or may not translate to humans. The summary is this:
– Stress can cause some symptoms of depression, but not all
– Some anti-depressants, when applied to stressed mice, helped reduce the symptoms
– When the suspect genes that allowed this pathway were removed from mice, the anti-depressant didn’t work.

Thoughts I have: Stress seems to prompt neurogenesis (the making of new brain cells and pathways), as do antidepressants. The two together make lots of neurogenesis.

So perhaps depression is a side effect of coping with change? Chronic depression may be the condition of being stuck in a “shut down” cycle as you adjust to change?

Hmm…

http://blogs.scientificamerican.com/scicurious-brain/2012/05/28/stress-and-antidepressants-by-their-powers-combined/